Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Maxam-Gilbert Sequencing01:05

Maxam-Gilbert Sequencing

13.4K
In the same year as the discovery of the Sanger sequencing method, another group of scientists, Allan Maxam and Walter Gilbert, demonstrated their chemical-cleavage method for DNA sequencing. The Maxam-Gilbert method relies on using different chemicals that can cleave the DNA sequence at specific sites, the separation of resulting DNA fragments of variable size using electrophoresis, and deciphering the DNA sequence from the resulting gel bands.
Challenges of the Maxam-Gilbert Method
The...
13.4K
Per-Unit Sequence Models01:26

Per-Unit Sequence Models

476
An ideal Y-Y transformer, grounded through neutral impedances, displays per-unit sequence networks akin to those of a single-phase ideal transformer when subjected to balanced positive- or negative-sequence currents. These currents do not produce neutral currents, and their associated voltage drops.
Zero-sequence currents, which are identical in magnitude and phase, generate a neutral current, resulting in voltage drops across the neutral impedance and the low-voltage winding. If the...
476
Signal Sequences and Sorting Receptors01:41

Signal Sequences and Sorting Receptors

15.7K
Signal sequences are short amino acid sequences that guide newly synthesized proteins to their proper location within the cell. Classical signal sequences are fifteen to sixty amino acids long and present at the N-terminus of a polypeptide chain. Each signal sequence has a conserved segment of basic residues towards their N terminus, a hydrophobic core, and a C-terminus rich in polar residues. The C-terminus also contains a signal cleavage site and features a -3 -1 sequence motif. The -3-1...
15.7K
Sequences01:29

Sequences

371
Sequences are fundamental mathematical objects consisting of ordered lists of numbers that follow a specific rule or pattern. Sequences are critical in various mathematical concepts, including calculus, series, and number theory. They can model real-world phenomena such as population growth, financial investments, and physical processes like the diminishing height of a bouncing ball.Each number in a sequence is referred to as a term. Typically, the terms are denoted as a1, a2, a3,…, where...
371
Sanger Sequencing01:57

Sanger Sequencing

776.7K
DNA sequencing is a fundamental technique that is routinely used in the biological sciences. This method can be applied to a range of questions at different scales - from the sequencing of a cloned DNA fragment or the study of a mutation in a gene up to whole-genome sequencing. However, despite the widespread use of sequencing today, it was not until 1977 that Fredrick Sanger and his collaborators developed the chain-termination method to decode DNA sequences. It relies on the separation of a...
776.7K
pV-Diagrams01:18

pV-Diagrams

6.4K
The pV diagram, which is a graph of pressure versus volume of the gas under study, is helpful in describing certain aspects of the substance. When the substance behaves like an ideal gas, the ideal gas equation describes the relationship between its pressure and volume. On a pV diagram, it is common to plot an isotherm, which is a curve showing p as a function of V with the number of molecules and the temperature fixed. Then, for an ideal gas, the product of the pressure of the gas and its...
6.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The dynamic interplay of merit and appreciation in love: Variations by gender, age, and relationship duration.

The Behavioral and brain sciences·2026
Same author

Reframing Expectations about aging - Physical Activity and Inclusive Reappraisal (RE-PAIR): Protocol of a randomized intervention promoting positive self-perceptions of aging and physical activity in older couples.

BMC geriatrics·2026
Same author

Old age is perceived to begin later: cross-European differences and the role of macro-level factors for the historical change in the perceived onset of old age.

The journals of gerontology. Series B, Psychological sciences and social sciences·2026
Same author

Aging in the city: Linking neighborhood features with whole-brain structural and micro-structural changes during aging.

Environmental research·2026
Same author

Age, preceding health changes, and the temporal structure of self-continuity.

Psychology and aging·2026
Same author

How a Mismatch Between Actual and Desired Fertility Relates to Well-Being Across Adulthood.

Journal of personality·2026
Same journal

Diagnosis of Alzheimer's disease and related dementias and outmigration of older Puerto Rican Medicare Fee-for-service beneficiaries, 2012-2019.

The journals of gerontology. Series B, Psychological sciences and social sciences·2026
Same journal

Inflammatory biomarkers are associated with spatial navigation in older adults.

The journals of gerontology. Series B, Psychological sciences and social sciences·2026
Same journal

Independent trajectories of cognitive function and daily events across nine years during midlife and old age.

The journals of gerontology. Series B, Psychological sciences and social sciences·2026
Same journal

Are associations between relationship satisfaction, emotional intimacy, and successful sexual aging gender-specific?

The journals of gerontology. Series B, Psychological sciences and social sciences·2026
Same journal

Bidirectional longitudinal associations of family/friend social support with cognitive function in late life.

The journals of gerontology. Series B, Psychological sciences and social sciences·2026
Same journal

How Do Limited Familial Ties and Community Relationships Shape Health-Seeking in Older Adulthood? Evidence from Indonesia.

The journals of gerontology. Series B, Psychological sciences and social sciences·2026
See all related articles

Related Experiment Video

Updated: Mar 9, 2026

Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance
04:58

Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance

Published on: December 13, 2024

4.4K

Analyzing Dyadic Data Using Grid-Sequence Analysis: Interdyad Differences in Intradyad Dynamics.

Miriam Brinberg1, Nilam Ram1,2, Gizem Hülür3

  • 1Department of Human Development and Family Studies, Pennsylvania State University, University Park.

The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
|December 31, 2016
PubMed
Summary
This summary is machine-generated.

Older couples exhibit distinct emotional dynamics. New grid-sequence analysis reveals four groups based on happiness patterns, offering insights into relationship health and potential interventions for aging couples.

Keywords:
Dyadic analysisExperience samplingInterpersonal dynamicsLongitudinal analysis

More Related Videos

Informatic Analysis of Sequence Data from Batch Yeast 2-Hybrid Screens
09:14

Informatic Analysis of Sequence Data from Batch Yeast 2-Hybrid Screens

Published on: June 28, 2018

7.6K
BEST: Barcode Enabled Sequencing of Tetrads
12:59

BEST: Barcode Enabled Sequencing of Tetrads

Published on: May 1, 2014

10.6K

Related Experiment Videos

Last Updated: Mar 9, 2026

Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance
04:58

Author Spotlight: Investigating the Role of Repetitive DNA Misregulation in Cancer Initiation and Immunotherapy Resistance

Published on: December 13, 2024

4.4K
Informatic Analysis of Sequence Data from Batch Yeast 2-Hybrid Screens
09:14

Informatic Analysis of Sequence Data from Batch Yeast 2-Hybrid Screens

Published on: June 28, 2018

7.6K
BEST: Barcode Enabled Sequencing of Tetrads
12:59

BEST: Barcode Enabled Sequencing of Tetrads

Published on: May 1, 2014

10.6K

Area of Science:

  • Gerontology
  • Psychology
  • Sociology

Background:

  • Spousal relationships significantly influence behavior, especially in later life.
  • Understanding dyadic dynamics is crucial for promoting well-being in older adults.

Purpose of the Study:

  • To introduce and validate a novel "grid-sequence" method for analyzing couple dynamics.
  • To identify distinct patterns of emotional and activity synchrony within older dyads.

Main Methods:

  • Employed a novel grid-sequence analysis combining state space grids and sequence analysis.
  • Utilized dyadic experience sampling data from 108 older couples (mean age 75.18).
  • Collected six daily emotion and activity reports over seven days per couple.

Main Results:

  • Identified four distinct groups of couples based on moment-to-moment happiness dynamics.
  • Observed associations between these patterns and dyad-level agreement on time spent together.
  • Found potential links to subjective health differences between couples.

Conclusions:

  • Grid-sequence analysis provides a robust method for examining dyadic microdynamics in older adults.
  • Identified dyadic patterns may serve as novel markers for risk or protective factors.
  • Findings suggest potential targets for interventions aimed at improving older adult relationships and well-being.