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Updated: Mar 9, 2026

Application of Microwave Ablation in Laparoscopic Partial Splenectomy
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Primary splenic lymphoma: Current diagnostic trends.

Sachin B Ingle1, Chitra R Hinge Ingle1

  • 1Sachin B Ingle, Department of Pathology, MIMSR Medical College, Latur, Maharashtra 4132512, India.

World Journal of Clinical Cases
|December 31, 2016
PubMed
Summary
This summary is machine-generated.

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Primary splenic lymphoma is rare and challenging to diagnose due to vague symptoms. Histopathology and immunohistochemistry are crucial for accurate diagnosis, with core biopsy/fine needle aspiration cytology offering a viable diagnostic approach.

Area of Science:

  • Hematology
  • Oncology
  • Pathology

Background:

  • Primary splenic lymphoma is an extremely rare malignancy.
  • It often presents with vague clinical signs, making diagnosis difficult.
  • Potential complications include hypersplenism and splenic rupture.

Discussion:

  • Histopathological examination and immunohistochemistry are essential for precise diagnosis.
  • Emergency splenectomy is a therapeutic and diagnostic tool for giant splenomegaly.
  • Core biopsy is generally contraindicated due to high vascularity and fragility, increasing complication risks.

Key Insights:

  • Core biopsy or fine needle aspiration cytology can serve as effective diagnostic tools.
  • Early and accurate diagnosis is vital to prevent severe disease and treatment complications.
Keywords:
BiopsyImmunohistochemistrySplenic lymphoma

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  • Anticoagulation therapy post-splenectomy is critical to prevent portal splenic vein thrombosis.
  • Outlook:

    • Further research into less invasive diagnostic methods for splenic lymphoma is warranted.
    • Improved diagnostic strategies can lead to earlier intervention and better patient outcomes.
    • Understanding the risks and benefits of different diagnostic procedures is crucial for clinical decision-making.