[Corrigendum] 5‑bromo-3-(3-hydroxyprop-1-ynyl)-2H-pyran-2‑one induces apoptosis in T24 human bladder cancer cells
Guo-Qiang Yu1, Zhong-Ling Dou1, Zhao-Hui Jia1
1Department of Urological Surgery, The First Affiliated Hospital, College of Clinical Medicine, Henan University of Science and Technology, Luoyang, Henan 471003, P.R. China.
Abstract:
Following the publication of this article, an interested reader drew to our attention that Fig. 1, which described the effects of 5-bromo-3-(3-hydroxyprop-1-ynyl)-2H-pyran-2-one (BHP) on T24 bladder carcinoma cell morphology and viability, contained a pair of panels showing identical data. After having re-examined our original data, we realize that the control data (showing 0 µM BHP) were inadvertently also included in Fig. 1 for the panel that was intended to show the effect of adding 10 µM BHP to the cells. A corrected version of Fig. 1, featuring the correct data for the addition of 10 µM BHP to the cells, is shown here. The error did not affect the conclusions reported in this study. We sincerely apologize for this mistake, and thank the reader of our article who drew this matter to our attention. Furthermore, we regret any inconvenience this mistake has caused. [the original article was published in the Molecular Medicine Reports 15: 153-159, 2016; DOI: 10.3892/mmr.2016.5991].
Insights
This correction clarifies the effects of 5-bromo-3-(3-hydroxyprop-1-ynyl)-2H-pyran-2-one (BHP) on T24 bladder carcinoma cells. The original Figure 1 erroneously duplicated control data, but the study
Area of Science:
- Oncology
- Molecular Biology
- Pharmacology
Background:
- Bladder carcinoma is a significant health concern.
- Investigating novel compounds for cancer treatment is crucial.
Purpose of the Study:
- To investigate the effects of 5-bromo-3-(3-hydroxyprop-1-ynyl)-2H-pyran-2-one (BHP) on T24 bladder carcinoma cells.
- To assess the impact of BHP on cell morphology and viability.
Main Methods:
- T24 bladder carcinoma cells were treated with varying concentrations of BHP.
- Cell morphology and viability were analyzed.
- Original data for Figure 1 was re-examined.
Main Results:
- A correction to Figure 1 is presented, showing the accurate effects of 10 µM BHP.
- The original Figure 1 contained duplicated control data.
- The error did not alter the study's conclusions.
Conclusions:
- The corrected data accurately reflects the impact of BHP on T24 bladder carcinoma cells.
- The study's original conclusions remain valid despite the data error.
More Related Videos
11:02Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
15:53Cell Death Associated with Abnormal Mitosis Observed by Confocal Imaging in Live Cancer Cells
Published on: August 21, 2013
Related Concept Videos
01:31The Intrinsic Apoptotic Pathway
01:30Apoptosis