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Sulbactam/ampicillin in the treatment of acute pelvic inflammatory disease
R L Sweet1, D V Landers, J Schachter
1Department of Obstetrics and Gynecology, University of California, San Francisco.
Supplement to International Journal of Gynecology and Obstetrics
|January 1, 1989
Abstract:
Acute pelvic inflammatory disease is associated with significant adverse reproductive sequelae. To prevent these serious sequelae, treatment regimens must cover the major etiologic agents which are Neisseria gonorrhoeae, Chlamydia trachomatis, and mixed anaerobic-aerobic bacteria. This report concerns the prospective evaluation of the efficacy of the combination of sulbactam with ampicillin in patients hospitalized with acute pelvic inflammatory disease. Clinical cure was noted in 33 (94%) of 35 patients and post-treatment cultures demonstrated eradication of N. gonorrhoeae and C. trachomatis in all cases.