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Related Experiment Videos

Influence of respiratory variations on right ventricular function.

J L Caplin1, W D Flatman, L Dyke

  • 1Department of Cardiology, St Bartholomew's Hospital, London.

British Heart Journal
|October 1, 1989
PubMed
Summary
This summary is machine-generated.

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Respiratory effort impacts right ventricular ejection fraction (RVEF). Expiration lowers RVEF, while the Valsalva maneuver increases it, suggesting respiratory influences on RV function.

Area of Science:

  • Cardiology
  • Physiology

Background:

  • Respiratory maneuvers, including inspiration, expiration, and the Valsalva maneuver, alter right ventricular (RV) preload and afterload.
  • These alterations are expected to influence RV systolic emptying and ejection fraction (RVEF).

Purpose of the Study:

  • To investigate the effects of maximal inspiration, expiration, and the Valsalva maneuver on resting right ventricular ejection fraction (RVEF).

Main Methods:

  • Resting RVEF was measured using first-pass radionuclide angiography with gold-195m.
  • Measurements were taken during maximal inspiration and expiration in 17 individuals.
  • Measurements were also taken at rest and during the strain phase of the Valsalva maneuver in 8 individuals.

Main Results:

Related Experiment Videos

  • RVEF was significantly lower during expiration compared to inspiration.
  • The Valsalva maneuver significantly increased RVEF, prolonged bolus duration, and increased RV transit time.
  • Valsalva maneuver data suggested the development of tricuspid regurgitation.

    • Conclusions:

    • Respiratory effort significantly affects RVEF, with expiration decreasing and the Valsalva maneuver increasing it.
    • Variations in venous return, pulmonary arterial pressure, pulmonary vascular resistance, and tricuspid regurgitation influence RVEF during respiratory maneuvers.
    • Changes in RV function during exercise assessed by first-pass radionuclide angiography should consider potential alterations in RVEF due to respiratory effort.