Related Experiment Video
Updated: Mar 9, 2026

A DNA/Ki67-Based Flow Cytometry Assay for Cell Cycle Analysis of Antigen-Specific CD8 T Cells in Vaccinated Mice
Published on: January 5, 2021
[Immunisation schedule of the Spanish Association of Paediatrics: 2017 recommendations]
Insights
The Spanish Association of Paediatrics recommends optimal childhood immunisation schedules, including funded vaccines like pneumococcal and varicella, and advises on unfunded options such as rotavirus and meningococcal vaccines.
Area of Science:
- Pediatrics
- Vaccinology
- Public Health
Background:
- The Spanish Association of Paediatrics' Advisory Committee on Vaccines (CAV-AEP) annually updates optimal childhood immunisation schedules for Spain.
- Key childhood vaccines like pneumococcal and varicella are funded in regional programmes.
- Recommendations extend to non-funded vaccines including rotavirus, meningococcal B, and meningococcal ACWY.
Purpose of the Study:
- To outline the CAV-AEP's recommended optimal immunisation schedule for children in Spain.
- To highlight funded and non-funded vaccination strategies.
- To provide evidence-based recommendations for vaccine administration timing and coverage.
Main Methods:
- Review of current evidence on vaccine efficacy and safety.
- Analysis of existing funded and recommended non-funded vaccination programmes in Spain.
- Formulation of a comprehensive immunisation schedule by the CAV-AEP.
Main Results:
- Recommended funded schedule: 2+1 strategy (2, 4, 11-12 months) for hexavalent (DTaP-IPV-Hib-HB) and 13-valent pneumococcal vaccines.
- Booster doses recommended for DTaP (6 years) and polio (Tdap vaccine for adolescents and pregnant women).
- Two-dose schedules for MMR (12 months, 2-4 years) and varicella (15 months, 2-4 years).
- Emphasis on improving human papillomavirus (HPV) vaccination coverage in 12-year-old girls and providing information to male adolescents.
- ACWY meningococcal vaccine recommended for adolescents.
- Meningococcal B vaccine recommended with a 3+1 scheme for unfunded immunisation.
- Rotavirus vaccination recommended for all infants.
Conclusions:
- The CAV-AEP provides an optimal immunisation schedule based on current evidence.
- Improvements are needed in HPV vaccination coverage and adolescent recommendations.
- The CAV-AEP advocates for the inclusion of meningococcal B vaccine in the funded schedule.
Abstract:
The Advisory Committee on Vaccines of the Spanish Association of Paediatrics (CAV- AEP) annually publishes the immunisation schedule which, in our opinion, is considered optimal for children resident in Spain, taking into account the evidence available on current vaccines. Pneumococcal and varicella immunisation in early childhood is already included in all funded vaccines present in the regional immunisation programmes. Furthermore, this committee establishes recommendations on vaccines not included in official calendars (non-funded immunisations), such as rotavirus, meningococcal B, and meningococcal ACWY. As regards funded immunisations, 2+1 strategy (2, 4, 11-12 months) with hexavalent (DTaP-IPV-Hib-HB) and 13-valent pneumococcal vaccines is recommended. Administration of the 6-year booster dose with DTaP is recommended, as well as a poliomyelitis dose for children who had received the 2+1 scheme, with the Tdap vaccine for adolescents and pregnant women between 27 and 32 weeks gestation. The two-dose scheme should be used for MMR (12 months and 2-4 years) and varicella (15 months and 2-4 years). Coverage of human papillomavirus vaccination in girls aged 12 with a two-dose scheme (0, 6 months) should be improved. Information and recommendations for male adolescents about potential beneficial effects of the tetravalent HPV vaccine should also be provided. ACWY meningococcal vaccine is the optimal choice in adolescents. For recommended unfunded immunisations, the CAV-AEP recommends the administration of meningococcal B vaccine, due to the current availability in Spanish community pharmacies, with a 3+1 scheme. CAV-AEP requests the incorporation of this vaccine in the funded unified schedule. Vaccination against rotavirus is recommended in all infants.
More Related Videos
07:33Conversion of Human Induced Pluripotent Stem Cells iPSCs into Functional Spinal and Cranial Motor Neurons Using PiggyBac Vectors
Published on: May 1, 2019
06:39Electroencephalographic, Heart Rate, and Galvanic Skin Response Assessment for an Advertising Perception Study: Application to Antismoking Public Service Announcements
Published on: August 28, 2017