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Updated: Mar 9, 2026

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
Published on: April 26, 2019
Matthew W Ralls1, Arnold G Coran2, Daniel H Teitelbaum1
1Department of Surgery, Section of Pediatric Surgery, University of Michigan, 1540 East Hospital Drive, Ann Arbor, Michigan, 48109-4211, USA.
Reoperative surgery for Hirschsprung disease (HSCR) is complex, addressing long-term complications after initial pullthrough procedures. Experienced teams are crucial for diagnosis, surgical correction, and follow-up in children with HSCR.
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