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Environmental Modulations of the Number of Midbrain Dopamine Neurons in Adult Mice
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Update on the use of immunoglobulin in human disease: A review of evidence

Elena E Perez1, Jordan S Orange2, Francisco Bonilla3

  • 1Allergy Associates of the Palm Beaches, North Palm Beach, Fla.

The Journal of Allergy and Clinical Immunology
|January 3, 2017
PubMed

Human immunoglobulin preparations for intravenous or subcutaneous administration are the cornerstone of treatment in patients with primary immunodeficiency diseases affecting the humoral immune system. Intravenous preparations have a number of important uses in the treatment of other diseases in humans as well, some for which acceptable treatment alternatives do not exist. We provide an update of the evidence-based guideline on immunoglobulin therapy, last published in 2006. Given the potential risks and inherent scarcity of human immunoglobulin, careful consideration of its indications and administration is warranted.

Keywords:
IGIVIVIGImmune globulinSCIGadverse eventsautoimmunityimmune modulatingimmunoglobulinimmunomodulationprimary immunodeficiencytransfusion

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