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Early repolarization pattern in the general population: Prevalence and associated factors
Guo-Zhe Sun1, Ning Ye1, Yin-Tao Chen1
1Department of Cardiovascular Medicine, The First Hospital of China Medical University, Shenyang, Liaoning 110001, China.
The early repolarization pattern (ERP) is uncommon in rural China, affecting 1.3% of adults. Key risk factors include younger age, male sex, and specific electrocardiographic findings.
Area of Science:
- Cardiology
- Epidemiology
- Public Health
Background:
- Early repolarization pattern (ERP) is an electrocardiographic finding with varying prevalence globally.
- Understanding ERP prevalence and associated factors in diverse populations is crucial for cardiovascular risk assessment.
Purpose of the Study:
- To determine the prevalence of ERP in a large, rural Chinese population.
- To identify independent clinical and electrocardiographic risk factors associated with ERP.
Main Methods:
- A cross-sectional study involving 11,956 residents aged 35 and older in Liaoning Province.
- ERP diagnosis based on J-point elevation criteria in specific ECG leads.
- Stepwise logistic regression analysis to identify risk factors.
Main Results:
- The overall prevalence of ERP was 1.3%, significantly higher in men (2.6%) than women (0.2%).
- Prevalence decreased with increasing age.
- Independent risk factors identified included younger age, male sex, lower systolic blood pressure, non-stroke history, longer RR interval, shorter QTc interval, shorter QRS duration, lower Cornell voltage, and higher Sokolow-Lyon voltage.
Conclusions:
- ERP prevalence is low in the studied rural Chinese population.
- Specific demographic and electrocardiographic factors are independently associated with ERP.
- These findings contribute to understanding ERP epidemiology in Asian populations.
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