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Updated: Mar 9, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
Quinolines: Microwave-assisted synthesis and their antifungal, anticancer and radical scavenger properties
Natália Aparecida Liberto1, Juliana Baptista Simões1, Sarah de Paiva Silva1
1Grupo de Química Supramolecular e Biomimética (GQSB), Departamento de Química, Universidade Federal de Viçosa, Viçosa, MG 36570-900, Brazil.
Abstract:
An efficient method for the synthesis of quinolines using microwave irradiation was developed providing 28 quinolines with good yields. The reaction procedures are environmentally friendly, convenient, mild and of easy work-up. Quinolines were evaluated for their antifungal, anticancer and antioxidant properties and exhibited high activities in all tests performed.
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