Effect of chronic stress on ENU-induced tumors
J Sotelo1, G Palencia, N Rosas
1Neuroimmunology Laboratory, National Institute of Neurology and Neurosurgery, Mexico City, Mexico.
Biological Psychiatry
|November 1, 1989
Abstract:
The relation of stress to cancer is the subject of considerable controversy. We studied the possible influence of chronic stress on the time of development and frequency of tumors induced in rats after a single exposure to ethylnitrosourea during prenatal life. Time of development, localization, incidence, type, and size of tumors were similar in stressed rats and in controls. Our results in this paradigm do not support the hypothesis that chronic stress exerts a potentiating effect on carcinogenesis.
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