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Pim1 kinase regulates c-Kit gene translation

Ningfei An1, Bo Cen2, Houjian Cai3

  • 1Department of Pathology, University of Chicago, Chicago, USA.

Experimental Hematology & Oncology
|January 3, 2017
PubMed
Summary

Pim1 kinase regulates c-Kit expression at the translational level, impacting hematopoietic stem cells and cancer treatment. Loss of Pim1 down-regulates c-Kit, affecting cell function.

Keywords:
HematopoiesisHematopoietic progenitor cellsHematopoietic stem cellsPIM kinaseReceptor tyrosine kinaseRegulationSerine/threonine kinaseTranslationc-Kit

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