[Angio-protective effect of catergen in experimental liver injury]

The 120 male rats were exposed to CCl4(1 mg/kg) or ethanol (6 g/kg) to produce acute liver injury. Previous injection of cathergen (+)-cyanidonol-3) decreased the region of hepatocytes necrosis, stabilized microvessels diameter and increased muss cells degranulation. These results indicate hepatoprotective and angioprotective effect of cathergen, more expressed in exposure CCl4.