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Obstructive sleep apnea and asthma
Megat Razeem Abdul Razak1, Naricha Chirakalwasan1
1Division of Pulmonary and Critical Care Medicine, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Insights
Treating obstructive sleep apnea (OSA) may improve asthma control in patients with both conditions. First-line OSA therapies like CPAP in adults and adenotonsillectomy in children show promise for alleviating asthma symptoms, warranting further research.
Area of Science:
- Respiratory Medicine
- Sleep Medicine
Background:
- Asthma and obstructive sleep apnea (OSA) are prevalent conditions affecting both pediatric and adult populations.
- A significant bidirectional relationship exists between asthma and OSA, with prevalence rates ranging from 38% to 70%.
Purpose of the Study:
- To review the pathogenesis of concomitant asthma and OSA.
- To evaluate if first-line OSA treatment improves asthma control in patients with both conditions.
Main Methods:
- Literature review examining the interplay between asthma and OSA.
- Analysis of existing evidence on the impact of OSA treatments on asthma symptoms.
Main Results:
- Growing evidence suggests that first-line OSA treatments can improve asthma symptoms.
- Continuous positive airway pressure (CPAP) in adults and adenotonsillectomy in children are identified as potentially beneficial.
Conclusions:
- Treating OSA may lead to better asthma control in patients with comorbid OSA and asthma.
- Larger randomized controlled trials are needed to confirm these findings and further evaluate treatment effects.
Abstract:
Both asthma and obstructive sleep apnea (OSA) are common conditions involving the adults and children population, and have significant impact on the healthcare system. For the last few decades a lot of data emerged in terms of the prevalence between asthma and OSA. The prevalence ranges from 38% up to as high as 70%. Based on the current concepts of bidirectional relationship of OSA and asthma, it is sensible to assume that treating one disorder will result in the other's better control and vice versa. This review will look into the pathogenesis of concomitant OSA and asthma and whether the first line OSA therapy will result in better control of asthma in patients with concomitant OSA. There is growing evidence that continuous positive airway pressure (CPAP) in adults and adenotonsillectomy in children which are recommended as first line treatment of OSA can improve their asthma symptoms. However, further confirmation is necessary with larger randomized control trials to further evaluate both conditions and the treatment effects.
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