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A High-throughput-compatible FRET-based Platform for Identification and Characterization of Botulinum Neurotoxin Light Chain Modulators
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A matrix-focused structure-activity and binding site flexibility study of quinolinol inhibitors of botulinum

William A Harrell1, Rebecca C Vieira1, Susan M Ensel2

  • 1Division of Molecular and Translational Sciences, U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, United States.

Bioorganic & Medicinal Chemistry Letters
|January 4, 2017
PubMed

Keywords:
Betti reaction productsBinding site flexibilityBoNT/A inhibitorBotulinum neurotoxin serotype AStructure-activity relationship

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