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Laparoscopic versus robotic adrenalectomy: A comprehensive meta-analysis.

Konstantinos P Economopoulos1, Konstantinos S Mylonas2, Aliki A Stamou3

  • 1Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Society of Junior Doctors, Athens, Greece.

International Journal of Surgery (London, England)
|January 4, 2017
PubMed
Summary

Robotic adrenalectomy (RA) and laparoscopic adrenalectomy (LA) show similar clinical outcomes, with RA offering a shorter hospital stay but longer operating times. Further research is needed to define RA's role and cost-effectiveness.

Keywords:
Laparoscopic adrenalectomyMeta-analysisRobot-assisted adrenalectomyRobotic adrenalectomy

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Area of Science:

  • Minimally Invasive Surgery
  • Surgical Oncology
  • Robotic Surgery

Background:

  • The comparative benefits of robotic adrenalectomy (RA) versus laparoscopic adrenalectomy (LA) remain under investigation.
  • Existing evidence is synthesized to assess which procedure yields superior clinical outcomes.

Purpose of the Study:

  • To systematically review and synthesize available evidence comparing robotic adrenalectomy (RA) to laparoscopic adrenalectomy (LA).
  • To evaluate the clinical outcomes of RA versus LA in adrenal surgery.

Main Methods:

  • A systematic literature search was conducted on PubMed and Scopus databases, adhering to PRISMA guidelines.
  • Data from 27 studies (13 comparative, 14 non-comparative) involving 1162 patients were extracted by three independent reviewers.
  • Perioperative variables were pooled using a random-effects model.

Main Results:

  • No significant differences were observed between RA and LA for intraoperative and postoperative complications, mortality, or blood loss.
  • Robotic adrenalectomy was associated with a significantly shorter hospital stay (WMD: -0.40 days).
  • Operating time was significantly longer for robotic adrenalectomy (WMD: 15.60 minutes).

Conclusions:

  • Robotic adrenalectomy is a safe and feasible alternative to laparoscopic adrenalectomy for selected patients.
  • Clinical outcomes are comparable between the two surgical approaches.
  • High-quality randomized controlled trials and standardized outcome reporting are necessary to establish the definitive role and cost-effectiveness of robotic adrenal surgery.