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Parental Obesity and Early Childhood Development
Edwina H Yeung1, Rajeshwari Sundaram2, Akhgar Ghassabian3
1Epidemiology Branch, yeungedw@mail.nih.gov.
Insights
Maternal and paternal obesity are linked to specific childhood developmental delays. This highlights the need to consider parental health information when assessing child development.
Area of Science:
- Pediatric Health
- Developmental Pediatrics
- Public Health
Background:
- Previous research linked maternal obesity to neurodevelopmental outcomes.
- Limited studies explored paternal obesity's distinct role in developmental programming.
- Parental obesity may influence child development through genetic and epigenetic pathways.
Purpose of the Study:
- To investigate the associations between maternal and paternal obesity and early childhood developmental delays.
- To examine specific developmental domains affected by parental obesity.
- To emphasize the importance of family health information in developmental screening.
Main Methods:
- Utilized data from the Upstate KIDS study (2008-2010).
- Included 3759 singletons and 1062 nonrelated twins with developmental data.
- Employed the Ages and Stages Questionnaire (ASQ) for developmental screening across multiple time points.
- Used generalized linear mixed models to analyze associations, adjusting for maternal covariates.
Main Results:
- Maternal obesity (BMI ≥30) was associated with increased odds of fine motor delays (aOR 1.67).
- Paternal obesity (29%) was linked to higher risk of personal-social domain delays (aOR 1.75).
- Children with both parents having BMI ≥35 showed increased risk for problem-solving delays (aOR 2.93).
Conclusions:
- Maternal and paternal obesity are independently associated with specific early childhood developmental delays.
- Findings underscore the significance of incorporating parental health status into developmental assessments.
- Family-level health data provides crucial context for understanding child development.
Background:
Previous studies identified associations between maternal obesity and childhood neurodevelopment, but few examined paternal obesity despite potentially distinct genetic/epigenetic effects related to developmental programming.
Methods:
Upstate KIDS (2008-2010) recruited mothers from New York State (excluding New York City) at ∼4 months postpartum. Parents completed the Ages and Stages Questionnaire (ASQ) when their children were 4, 8, 12, 18, 24, 30, and 36 months of age corrected for gestation. The ASQ is validated to screen for delays in 5 developmental domains (ie, fine motor, gross motor, communication, personal-social functioning, and problem-solving ability). Analyses included 3759 singletons and 1062 nonrelated twins with ≥1 ASQs returned. Adjusted odds ratios (aORs) and 95% confidence intervals were estimated by using generalized linear mixed models accounting for maternal covariates (ie, age, race, education, insurance, marital status, parity, and pregnancy smoking).
Results:
Compared with normal/underweight mothers (BMI <25), children of obese mothers (26% with BMI ≥30) had increased odds of failing the fine motor domain (aOR 1.67; confidence interval 1.12-2.47). The association remained after additional adjustment for paternal BMI (1.67; 1.11-2.52). Paternal obesity (29%) was associated with increased risk of failing the personal-social domain (1.75; 1.13-2.71), albeit attenuated after adjustment for maternal obesity (aOR 1.71; 1.08-2.70). Children whose parents both had BMI ≥35 were likely to additionally fail the problem-solving domain (2.93; 1.09-7.85).
Conclusions:
Findings suggest that maternal and paternal obesity are each associated with specific delays in early childhood development, emphasizing the importance of family information when screening child development.
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