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Updated: Mar 9, 2026

Author Spotlight: Decellularization-Based Quantification of Skeletal Muscle Fatty Infiltration
Published on: June 9, 2023
Effect of aging on region-specific functional role and muscle geometry along human rectus femoris muscle
Kohei Watanabe1, Motoki Kouzaki2, Toshio Moritani3
1Laboratory of Neuromuscular Biomechanics, School of International Liberal Studies, Chukyo University, Yagotohonmachi, Showa-ku, Nagoya, 466-8666, Japan.
Introduction:
We compared the region-specific neuromuscular activation and muscle morphology along the rectus femoris (RF) muscle between young and elderly.
Methods:
Ratios of surface electromyography amplitude between hip flexion and knee extension (HF/KE) were compared among regions along the muscle for 9 young and 9 elderly men. Muscle thickness was also compared among the regions.
Results:
HF/KE in the proximal region was significantly greater than in the middle and distal regions for both the young and elderly (P < 0.05). However, a significant difference in HF/KE between the middle and distal regions was found in the young (P < 0.05), but not in the elderly (P > 0.05). A difference in the region-specific muscle thickness was observed between the young and elderly.
Conclusion:
These findings suggest that functional role and muscle morphology are regionally affected by aging along the RF muscle. Muscle Nerve 56: 982-986, 2017.
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