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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

339
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

298
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Dementia01:30

Dementia

633
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
633
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

781
As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
781
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

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In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
300
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

307
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
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Related Experiment Video

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Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
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[Geriatric psychiatry and dementia].

Philippe Fernandez1

  • 1Équipe mobile intersectorielle de psychiatrie du sujet âgé (Emipsa), Centre hospitalier Gérard-Marchant134 route d'Espagne, 31057 Toulouse, France.

Revue De L'Infirmiere
|January 4, 2017
PubMed
Summary

Behavioral disorders are common in dementia, presenting complex challenges for caregivers. Geriatric psychiatry expertise aids in understanding symptoms and guiding patient support strategies.

Keywords:
Alzheimer's diseasebehavioural disorderdementiadémencegeriatric psychiatrygérontopsychiatriemaladie d’Alzheimertrouble du comportement

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Area of Science:

  • Geriatric Psychiatry
  • Neurodegenerative Diseases
  • Behavioral Health

Background:

  • Behavioral disorders frequently co-occur with dementia.
  • The combination of psychiatric and neurodegenerative conditions creates complex care scenarios for individuals and their families.
  • Caregivers often face significant daily challenges managing these intertwined pathologies.

Purpose of the Study:

  • To highlight the importance of geriatric psychiatry expertise in managing dementia-related behavioral disorders.
  • To emphasize the need for effective nursing approaches to understand and support patients.
  • To guide clinical reasoning in complex psychiatric and neurodegenerative cases.

Main Methods:

  • Clinical case review and analysis.
  • Expert consultation and guidance from geriatric psychiatry teams.
  • Development of evidence-based nursing interventions.

Main Results:

  • Geriatric psychiatry expertise is crucial for accurate diagnosis and treatment planning.
  • Structured nursing approaches improve patient understanding and support.
  • Multidisciplinary collaboration enhances management of complex behavioral symptoms.

Conclusions:

  • Integrated care models incorporating geriatric psychiatry are essential for dementia patients with behavioral disorders.
  • Specialized nursing interventions are key to improving patient outcomes and caregiver support.
  • Understanding the interplay between psychiatric and neurodegenerative factors is vital for effective patient management.