Preparing Brain Slices to Study Basic Synaptic Properties
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Updated: Mar 9, 2026

Vibrodissociation of Neurons from Rodent Brain Slices to Study Synaptic Transmission and Image Presynaptic Terminals
Published on: May 25, 2011
1Department of Biological Sciences, University at Buffalo, State University of New York, Buffalo, New York 14260.
Abstract:
This protocol describes how to prepare brain slices for electrophysiology, with an emphasis on synaptic physiology in voltage clamp. This approach remains the gold standard for understanding the properties of individual neurons, as well as the connections between neurons.
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