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Morphometric Study of Pancreas in Human Fetuses
Abhijeet S Dhende1, Mahendra A Kathole2, Deepak S Joshi3
1Assistant Professor, Department of Anatomy, Seth G.S. Medical College & K.E.M. Hospital , Mumbai, Maharashtra, India .
Journal of Clinical and Diagnostic Research : JCDR
|January 5, 2017
Summary
Human pancreas morphometry was studied in fetuses aged 12-40 weeks. Pancreas length and head height significantly increase with gestational age, crucial for understanding pancreatic development.
Area of Science:
- Developmental biology
- Human anatomy
- Medical research
Background:
- The pancreas, an endocrine and exocrine organ, develops from dorsal and ventral endodermal buds.
- It is situated across the posterior abdominal wall, extending from the duodenum to the spleen.
Purpose of the Study:
- To investigate the morphometric characteristics of the human pancreas.
- To analyze pancreatic dimensions across various gestational age groups in fetuses.
Main Methods:
- Study included 40 aborted human fetuses (25 male, 15 female) aged 12-40 weeks.
- Fetuses were dissected to isolate the pancreas for measurement.
- Key parameters measured: pancreas length, pancreas weight, and pancreatic head height.
Main Results:
- Significant positive correlation observed between gestational age and fetal body weight/crown rump length.
- Average pancreas length increased from 1.80 cm at 12 weeks to 4.70 cm at 40 weeks gestation.
- Average pancreatic head height increased from 0.80 cm at 12 weeks to 2.70 cm at 40 weeks gestation.
Conclusions:
- Established morphometric data for the developing human pancreas.
- Understanding pancreatic development is vital for addressing congenital and functional pancreatic anomalies.
- This research aids in planning future therapeutic strategies for pancreatic disorders.
