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Related Concept Videos

Pharmacovigilance01:19

Pharmacovigilance

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Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
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Bioequivalence studies: Biowaivers01:13

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In certain scenarios, in vitro dissolution tests can replace in vivo bioequivalence studies. This is particularly true when a drug product, though available in varying strengths, maintains proportional similarity in its active and inactive ingredients. In such cases, the need for in vivo bioequivalence studies for lower strength variants may be waived, provided dissolution tests and in vivo studies on the highest strength yield satisfactory results.Bioequivalence can be indicated through...
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Principles of Disease Surveillance01:26

Principles of Disease Surveillance

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Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
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Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

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Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
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Vaccinations01:51

Vaccinations

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Overview
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Therapeutic Drug Monitoring: Affecting Factors01:29

Therapeutic Drug Monitoring: Affecting Factors

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Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
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Haemovigilance: A Current Update in Indian Perspective.

Somnath Mukherjee1, Rituparna Maiti2

  • 1Associate Professor, Department of Transfusion Medicine, All India Institute of Medical Sciences , Bhubaneswar, Odisha, India .

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Summary

Haemovigilance systems monitor blood transfusion safety globally. India

Keywords:
Adverse reactionBlood usageImputabilityTransfusion practice

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Area of Science:

  • Pharmacovigilance and public health.
  • Blood product safety and transfusion medicine.

Background:

  • Haemovigilance is crucial for monitoring adverse events in blood transfusion and manufacturing.
  • It ensures quality control, implementing corrective measures for blood product safety.
  • Global adoption of haemovigilance systems highlights its importance in developed nations.

Conclusions:

  • Haemovigilance is essential for ensuring the safety and quality of blood products.
  • The Haemovigilance Program of India is a key initiative for monitoring transfusion safety.
  • Continuous monitoring and intervention are necessary for advancing patient care in transfusion medicine.