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Factors associated with corneal epithelial defects after pars plana vitrectomy
Wei-Yu Chiang1, Jong-Jer Lee1, Hsi-Kung Kuo1
1Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung City, 83301, Taiwan.
International Ophthalmology
|January 5, 2017
Summary
Pars Plana Vitrectomy (PPV) can cause corneal epithelial defects (CED), especially in patients with diabetes mellitus (DM) and rhegmatogenous retinal detachment (RRD). DM patients also face a higher risk of delayed corneal healing after PPV surgery.
Area of Science:
- Ophthalmology
- Surgical Outcomes
- Corneal Health
Background:
- Corneal epithelial defects (CED) are a potential complication following ophthalmic surgery.
- Understanding risk factors for CED and delayed healing after pars plana vitrectomy (PPV) is crucial for patient management.
Purpose of the Study:
- To identify risk factors for corneal epithelial defects (CED) after pars plana vitrectomy (PPV).
- To investigate factors associated with delayed corneal healing (exceeding one week) post-PPV.
Main Methods:
- Retrospective study of 255 patients undergoing PPV between 2011-2012.
- Analysis of demographic data, underlying diseases, surgical indications, operative parameters, and CED occurrence.
- Statistical evaluation of factors linked to CED and delayed healing.
Main Results:
- Corneal epithelial defects (CED) occurred in 23.1% of patients post-PPV.
- CED was associated with younger age, diabetes mellitus (DM), rhegmatogenous retinal detachment (RRD), longer surgery duration, and silicon oil use.
- Delayed healing (over 1 week) was observed in 11.9% of CED cases, with a higher incidence in patients with DM.
Conclusions:
- Rhegmatogenous retinal detachment (RRD), prolonged surgery, and diabetes mellitus (DM) are risk factors for developing corneal epithelial defects (CED) after PPV.
- Diabetes mellitus (DM) is linked to a higher incidence of delayed corneal healing post-pars plana vitrectomy.
