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Published on: July 6, 2016
Quinoline-Derived Two-Photon Sensitive Quadrupolar Probes
Christine Tran1, Nawel Berqouch1, Hamid Dhimane1
1Laboratoire de Chimie et Biochimie, Pharmacologiques et Toxicologiques, Université Paris Descartes, 45, rue des Saints-Pères, 75270, Paris Cedex 06, France.
Abstract:
Quadrupolar probes derived from 8-dimethylamino-quinoline (8-DMAQ) having a pegylated fluorene core were prepared and studied under "one-photon" (λ=365 nm) and "two-photon" (TP) (λ=730 nm) irradiation conditions. Compound 1 a was identified as the most efficient probe by UV activation that showed sequential release of acetic acid as a model. Although the probe showed high two-photon absorption it stayed inert under femtosecond irradiation conditions. Fast and selective photolysis was observed, however, by using picosecond irradiation conditions with a remarkably high TP uncaging cross-section (δu =2.3 GM).
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