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Updated: Mar 9, 2026

An In-vitro Preparation of Isolated Enteric Neurons and Glia from the Myenteric Plexus of the Adult Mouse
Published on: August 7, 2013
XIVth Little Brain Big Brain: next-generation enteric neuroscience
Arthur Beyder1, Guillaume de Lartigue2, Jean-Eric Ghia3
1Enteric Neuroscience Program, Division of Gastroenterology &Hepatology, Department of Physiology &Biomedical Engineering, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905, USA.
The Little Brain Big Brain meeting showcases young neurogastroenterology researchers. The XIVth meeting highlighted new ideas in gut motility, inflammation, and metabolism.
Area of Science:
- Neurogastroenterology
- Gastrointestinal Motility
- Gut Inflammation
- Metabolism
Background:
- The Little Brain Big Brain is a biannual meeting for young investigators in neurogastroenterology.
- This meeting has been held since 1989, fostering a community of early-career scientists.
- It focuses on advancing research in the gut-brain axis.
Purpose of the Study:
- To summarize the key research presented at the XIVth Little Brain Big Brain meeting.
- To highlight novel hypotheses and cutting-edge work in neurogastroenterology.
- To emphasize the meeting's focus on motility, inflammation, and metabolism.
Main Methods:
- The XIVth meeting featured presentations by young investigators.
- Discussions centered on novel hypotheses and recent advancements.
- Thematic sessions covered motility, inflammation, and metabolism.
Main Results:
- Cutting-edge research was presented across the main themes.
- Novel hypotheses were advanced in gut motility.
- New insights into gut inflammation and metabolism were explored.
Conclusions:
- The XIVth Little Brain Big Brain meeting successfully advanced novel hypotheses.
- The meeting underscored the dynamic progress in neurogastroenterology.
- Future research directions in motility, inflammation, and metabolism were indicated.
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