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Optimization of formulation and processing of Moringa oleifera and spirulina complex tablets
1School of Biological and Chemical Engineering, Panzhihua University, Panzhihua 617000, China; Key Laboratory of Dry-hot Valley Characteristic Bio-Resources Development of University of Sichuan Province, Panzhihua 617000, China.
Saudi Journal of Biological Sciences
|January 6, 2017
Summary
This study developed balanced nutrition tablets using Moringa oleifera and spirulina. Optimized formulations ensure comprehensive nutritional benefits and meet quality standards for a natural dietary supplement.
Area of Science:
- Nutritional Science
- Pharmacognosy
- Food Technology
Background:
- Moringa oleifera and spirulina are nutrient-dense natural ingredients.
- Combining these offers complementary nutritional profiles for enhanced supplements.
- Optimizing their ratio and formulation is key for effective delivery.
Purpose of the Study:
- To develop a comprehensive and balanced nutritional supplement tablet.
- To determine the optimal ratio of Moringa oleifera leaves and spirulina.
- To optimize the formulation and preparation process for Moringa oleifera and spirulina complex tablets.
Main Methods:
- Nutrient composition analysis of Moringa oleifera and spirulina.
- Single factor and orthogonal experiments to determine optimal raw material ratios and excipients (microcrystalline cellulose, CMC, magnesium stearate).
- Powder direct compression technology used for tablet preparation.
Main Results:
- The optimal raw material ratio was determined to be 7:3 (Moringa oleifera powder: spirulina powder).
- The best tablet formulation included 88.5% raw materials, 8.0% microcrystalline cellulose, 2.0% CMC, and 1.5% magnesium stearate.
- Optimum processing parameters included 200-300 mesh particle size, 7% moisture content, and 40 kN tableting pressure.
Conclusions:
- Optimized formulation and process yield comprehensive and balanced nutrition complex tablets.
- The prepared Moringa oleifera and spirulina tablets meet appropriate quality requirements for appearance, weight variation, hardness, friability, and disintegration.
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