Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Rabies01:28

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical presentation domains and venous anatomical patterns in cerebral venous thrombosis: a retrospective cohort study.

BMC neurology·2026
Same author

EBV viral load and miR-BART10-3p expression in multiple sclerosis: A case-control study.

Multiple sclerosis and related disorders·2026
Same author

Investigating Depression and MRI Associations in Middle Eastern Relapsing-Remitting Multiple Sclerosis.

Journal of biomedical physics & engineering·2026
Same author

Cost-Effectiveness of Dimethyl Fumarate Versus Teriflunomide in Patients With Relapsing-Remitting Multiple Sclerosis (RRMS) in Iran.

Health science reports·2026
Same author

An Artificial Intelligence-Based Screening Tool for Detection of Cerebral Venous Thrombosis on Non-Contrast Brain CT.

Cerebrovascular diseases (Basel, Switzerland)·2026
Same author

Advancements in Pharmacotherapy and Mobile Health Applications for Self-Management in Multiple Sclerosis: A Comprehensive Review.

Recent patents on biotechnology·2026

Related Experiment Video

Updated: Jul 7, 2026

Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells
15:29

Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells

Published on: August 5, 2016

8.7K

Neurobrucellosis Presented with a Hyperacute Onset: A Case Report.

Arefeh Khademi1, Maryam Poursadeghfard2, Reza Nikandish Noubar3

  • 1Dept. of Neurology, Medical School, Shiraz University of Medical Sciences, Shiraz, Iran.

Iranian Journal of Public Health
|January 6, 2017
PubMed
Summary

Neurobrucellosis, a rare complication of brucellosis, can present with varied neurological symptoms. Early consideration in endemic areas is crucial for timely diagnosis and management of this challenging condition.

Keywords:
Hyperacute onsetIranNeurobrocellosisNeurologic manifestation

More Related Videos

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

16.6K
Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
06:23

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

5.5K

Related Experiment Videos

Last Updated: Jul 7, 2026

Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells
15:29

Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells

Published on: August 5, 2016

8.7K
A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

16.6K
Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
06:23

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

5.5K

Area of Science:

  • Neurology
  • Infectious Diseases
  • Public Health

Background:

  • Neurobrucellosis is an uncommon but significant complication of brucellosis.
  • It can manifest with diverse neurological symptoms at any disease stage.
  • Diagnosis relies on clinical history, physical examination, and laboratory findings.

Purpose of the Study:

  • To report a case of neurobrucellosis with an unusual hyperacute presentation.
  • To emphasize the importance of considering neurobrucellosis in unexplained neurological cases in endemic regions.

Main Methods:

  • Case report of a 25-year-old woman diagnosed with neurobrucellosis.
  • Clinical presentation, diagnostic process, and management are described.

Main Results:

  • The patient presented with a hyperacute onset of headache and abnormal behavior.
  • Diagnosis of neurobrucellosis was confirmed.
  • The case highlights the varied clinical spectrum of neurobrucellosis.

Conclusions:

  • Neurobrucellosis requires a high index of suspicion, especially in endemic areas.
  • Prompt diagnosis and management are essential despite the slow response to treatment.