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Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
[Cardiac surgery in the elderly]
B Wiegmann1, I Ismail2, A Haverich2
1Klinik für Herz-, Throax-, Transplatations- und Gefäßchirurgie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland. wiegmann.bettina@mh-hannover.de.
Insights
Elderly patients, including those over 80, benefit from cardiac surgery. Biological age and comorbidities are key, not chronological age, with elective procedures yielding better outcomes and improved quality of life.
Area of Science:
- Cardiology
- Geriatric Medicine
- Surgical Outcomes
Background:
- Cardiovascular diseases are a leading cause of death.
- The average age of patients undergoing cardiac surgery is increasing.
- 14.8% of cardiac surgery patients were over 80 in 2015.
Purpose of the Study:
- To evaluate the benefits of cardiac surgery for elderly patients.
- To determine circumstances where elderly patients can undergo surgery without compromising quality of life.
- To assess risks of morbidity and mortality in older cardiac surgery patients.
Main Methods:
- Meta-analysis of existing studies.
- Review of perioperative and postoperative outcomes.
- Comparison of outcomes based on chronological vs. biological age.
Main Results:
- Chronological age is not a significant risk factor for morbidity/mortality.
- Biological age, comorbidities, and disease stage are critical factors.
- Elective surgeries show better outcomes than those in symptomatic/decompensated stages.
- Elderly patients experience improved life expectancy and quality of life post-surgery, comparable to younger patients.
Conclusions:
- Elderly patients, even those over 80, benefit significantly from cardiac surgery.
- Individualized surgical techniques are crucial for optimal outcomes in older adults.
- Cardiac surgery improves life expectancy and quality of life for elderly patients compared to conventional therapy.
Abstract:
Due to the increasing demographic changes and the fact that cardiovascular diseases are still the leading cause of death, the mean chronological age of patients undergoing cardiac surgery is steadily increasing. In 2015, 14.8% of these patients were aged 80 years and older. This meta-analysis reviewed if and under what circumstances elderly patients benefit from cardiac surgical procedures without running the risk of limitations in the quality of life and high rates of morbidity and mortality. Generally, the chronological age was not a risk factor for higher perioperative and postoperative morbidity and mortality but the biological age was the critical factor, in particular the associated comorbidities of patients and the timing of the surgical procedure in the course of the disease. The result is that elective operations resulted in a better outcome than operations in a symptomatic or decompensated stage of a disease. Compared to patients receiving conventional medicinal therapy, elderly patients undergoing cardiac surgery had an improved life expectancy. A significant increase in the quality of life could also be identified and was ultimately comparable to those of younger patients after cardiac surgery; therefore, elderly patients even those over 80 years old benefit in all aspects of cardiac surgery, as long as individually adapted operative techniques are considered.
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