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Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
[Chronic subdural hematoma in the elderly]
T A Juratli1, J Klein2, G Schackert2
1Klinik und Poliklinik für Neurochirurgie, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Deutschland. tareq.juratli@uniklinikum-dresden.de.
Insights
Chronic subdural hematoma (cSDH) is a common condition, often requiring surgery. While surgical outcomes are generally good, even in older adults, further research is needed on potential pharmacological treatments.
Area of Science:
- Neurosurgery
- Geriatric Medicine
Background:
- Chronic subdural hematoma (cSDH) is increasingly prevalent due to aging populations and antithrombotic drug use.
- cSDH presents with non-specific symptoms and neurological deficits, typically necessitating surgical intervention.
Purpose of the Study:
- To review the current management and outcomes of chronic subdural hematoma.
- To highlight the need for further investigation into adjunctive pharmacological therapies for cSDH.
Main Methods:
- Review of current surgical standards for cSDH, including burr hole trepanation and twist drill craniostomy.
- Discussion of recurrence rates and outcomes in elderly patients with cSDH and comorbidities.
Main Results:
- Surgical treatment, primarily minimally invasive procedures, is the standard for cSDH.
- Recurrences are common but often manageable, with good outcomes achievable even in elderly patients.
- cSDH is associated with increased morbidity and mortality, particularly in patients with comorbidities.
Conclusions:
- Current surgical approaches for cSDH are effective, with good outcomes in most cases, including the elderly.
- Further controlled trials are required to evaluate the efficacy of pharmacological therapies as an adjunct to surgery for cSDH.
Abstract:
Chronic subdural hematoma (cSDH) is a common condition, the frequency of which further increases due to an aging population and more frequent use of antithrombotic drugs. It leads to unspecific symptoms and neurological deficits and is usually treated surgically. Burr hole trepanation and twist drill craniostomy have become the therapeutic standards with craniotomy being rarely used for recurrent cases. Although recurrences are relatively common, in most cases a good outcome can be achieved even in the elderly; however, as cSDH is associated with other comorbidities, it is indicative of an increased morbidity and mortality. Controlled trials need to be carried out to determine whether pharmacological therapies can also be beneficial in addition to surgical treatment.
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