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Published on: December 20, 2024
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Transduodenal ampullectomy for ampullary tumors
Verushka M Mansukhani1, Gunjan S Desai1, Sasi Mouli1
1Department of Surgical Oncology, Lilavati Hospital and Research Centre, A 791, Bandra West, Mumbai, 400 050, India.
Summary
Transduodenal ampullectomy (TDA) is a safe procedure for benign ampullary tumors. This study found TDA effective with a low recurrence rate for selected patients.
Area of Science:
- Gastroenterology
- Surgical Oncology
Background:
- Ampullary tumors require careful management due to potential for malignancy.
- Transduodenal ampullectomy (TDA) is an option for specific ampullary pathologies.
Purpose of the Study:
- To evaluate the safety and efficacy of Transduodenal ampullectomy (TDA).
- To assess outcomes for patients undergoing TDA for ampullary tumors.
Main Methods:
- Retrospective review of 11 patients who underwent TDA between 2009 and 2015.
- Preoperative investigations included MRI-MRCP, CECT, side-viewing endoscopy, and EUS.
- All patients had preoperative biopsy for diagnosis.
Main Results:
- Only one recurrence was observed among the 11 patients.
- Two patients with adenocarcinoma underwent subsequent pancreaticoduodenectomy.
- TDA demonstrated a low recurrence rate in well-selected cases.
Conclusions:
- Transduodenal ampullectomy (TDA) is a safe surgical option for selected benign ampullary pathologies.
- TDA is a viable treatment for ampullary adenomas not suitable for endoscopic resection.

