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Anatomy of the Brain: Major Regions

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Related Experiment Video

Updated: Mar 9, 2026

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

Within brain area tractography suggests local modularity using high resolution connectomics.

Peter N Taylor^1,2,3, Yujiang Wang², Marcus Kaiser^1,2

¹Institute of Neuroscience, Newcastle University, United Kingdom.

Scientific Reports

|January 6, 2017

Summary

This summary is machine-generated.

This study reveals a hierarchical organization in high-resolution brain networks, showing modules within brain areas are spatially localized. This structure may underpin functional specialization within the brain.

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Last Updated: Mar 9, 2026

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

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DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions

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Published on: August 26, 2014

Area of Science:

Neuroscience
Computational Neuroscience
Network Science

Background:

Previous brain connectivity studies focused on macroscopic scales (around 1,000 nodes).
Recent advances enable reproducible high-resolution connectomes (around 50,000 nodes).

Purpose of the Study:

To infer high-resolution brain connectivity matrices.
To analyze networks within brain areas at the individual subject level.
To investigate the topological organization and modular architecture of high-resolution brain networks.

Main Methods:

Utilized diffusion imaging data from the Human Connectome Project.
Inferred high-resolution structural brain connectivity matrices.
Analyzed network properties at a fine-grained scale within individual subjects.

Main Results:

The global brain network exhibits scale-invariant topological organization.
A hierarchical organization of modular architecture was identified.
Modules within brain areas were found to be spatially localized.
Long-range connections terminate between specific modules, while short-range connections terminate within modules.

Conclusions:

High-resolution brain connectivity reveals a hierarchical and spatially organized modular architecture.
The spatial localization of white matter modules may correspond to cytoarchitecturally distinct grey matter areas.
This modular organization likely serves as the structural basis for functional specialization within brain areas.
Future research should explore how neurological diseases impact this intra-areal modular architecture.