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Updated: Mar 9, 2026

Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury
Published on: August 14, 2019
Bilateral Hippocampal Restricted Diffusion: Same Picture Many Causes
Shamik Bhattacharyya1, Taha Gholipour1, Rene A Colorado1
1Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
Abstract:
With some regularity, we have encountered the unusual imaging abnormality of bilateral hippocampal restricted diffusion, either in isolation or in combination with other coincident abnormalities. In this retrospective case series, we examine clinical and imaging data to explore potential etiologies and clinical implications of this imaging finding. Sixteen cases with the imaging abnormality are presented, with etiologies including hypoxemia, hypoxemia-ischemia, and seizures.

