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Human Rabies - Puerto Rico, 2015.

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    A 54-year-old man died from rabies after a mongoose bite in Puerto Rico. Prompt postexposure prophylaxis (PEP) was initiated for five family members following confirmation of the human rabies case.

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    Area of Science:

    • Public Health
    • Infectious Diseases
    • Veterinary Medicine

    Background:

    • Rabies is a fatal viral disease transmitted primarily through animal bites.
    • Early diagnosis and prompt postexposure prophylaxis (PEP) are critical for preventing rabies.
    • Mongoose populations can act as reservoirs for rabies virus in endemic areas.

    Observation:

    • A 54-year-old man presented with symptoms consistent with rabies, including fever, dysphagia, and paresthesia.
    • The patient reported a mongoose bite weeks prior, for which he did not seek medical attention.
    • The patient experienced rapid clinical deterioration, leading to cardiac arrest and death.

    Findings:

    • Rabies virus was confirmed in autopsy specimens from the deceased patient.
    • The case highlighted a potential gap in rabies awareness and timely medical care seeking after animal bites.
    • Public health authorities initiated a rapid risk assessment and administered PEP to close contacts.

    Implications:

    • This case underscores the importance of public education regarding animal bite management and rabies prevention.
    • Timely administration of rabies postexposure prophylaxis is crucial in preventing human rabies deaths.
    • Surveillance of rabies in mongoose populations is essential for informing public health interventions.