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Modified Vaccinia Virus Ankara: History, Value in Basic Research, and Current Perspectives for Vaccine Development
1German Center for Infection Research (DZIF), Institute for Infectious Diseases and Zoonoses, LMU University of Munich, Munich, Germany.
Advances in Virus Research
|January 7, 2017
Summary
Modified Vaccinia virus Ankara (MVA) is a safe and effective vaccine vector for infectious diseases and cancer. Its unique properties make it a versatile tool for developing novel vaccines against various global health threats.
Area of Science:
- Virology
- Immunology
- Vaccinology
Background:
- Modified Vaccinia virus Ankara (MVA) is a third-generation smallpox vaccine and a well-established viral vector.
- MVA was developed through extensive cell culture passage, resulting in a virus attenuated for mammalian replication.
- Its biological characteristics facilitate research into poxvirus host interactions.
Keywords:
Emergency vaccinesInfectious diseasesPoxvirusSmallpox vaccineVaccine developmentViral vector vaccinesVirus–host interactionZoonosesMore Related Videos
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