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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Stratified epithelium consists of several stacked layers of cells. They provide the durability to withstand constant physical and chemical attacks. Stratified epithelium is named after the shape of the most apical layer of cells. Stratified squamous epithelium is the most common type found in the human body. In this tissue, the apical cells are squamous, whereas the basal layer contains either columnar or cuboidal cells. The basal cells divide to form new daughter cells, which gradually become...
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The epidermis is made of four or five layers of epithelial cells, depending on its location in the body. From deep to superficial, these layers are the stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum.
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Accessory Structures of the Skin: Hair Growth and Types01:20

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Hair growth begins with the production of keratinocytes by the basal cells of the hair bulb. As new cells are deposited at the hair bulb, the hair shaft is pushed through the follicle toward the surface. Keratinization is completed as the cells are pushed to the skin surface to form the shaft of hair that is externally visible. The external hair is completely dead and composed entirely of keratin. Hair can be cut or shaven without damaging the hair structure because the cut is superficial. Most...
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Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
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Basosquamous carcinoma: appearance and reality.

Rakesh L Anand1, Damian Collins2, Anna Chapman1

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|January 7, 2017
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Summary

Basosquamous carcinoma (BsC), a rare tumor with mixed basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) features, presents diagnostic and therapeutic challenges. Early diagnosis is crucial due to its aggressive nature and potential for metastasis.

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Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Basosquamous carcinoma (BsC) is a rare skin neoplasm with controversial classification.
  • It exhibits mixed histopathological features of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC).
  • BsC presents diagnostic and therapeutic challenges due to variable morphology and unpredictable behavior.

Observation:

  • This report details a case of BsC presenting as an extensive ulcer on the back.
  • The presentation highlighted the tumor's aggressive nature and varied appearance.
  • The case underscores the importance of recognizing BsC's clinical presentation.

Findings:

  • BsC demonstrates aggressive behavior, a higher likelihood of recurrence, and potential for metastasis.
  • Accurate histopathological diagnosis is essential for effective management.
  • Timely biopsy in specialized clinics is critical for prompt diagnosis and treatment.

Implications:

  • Increased clinical awareness of BsC is necessary for early detection.
  • Prompt diagnosis and adequate biopsy in specialist settings are vital.
  • Understanding BsC's aggressive potential guides treatment strategies and improves patient outcomes.