Zika virus disease for neurologists
Daniel E Smith1, J David Beckham1, Kenneth L Tyler1
1Neuro-Infectious Diseases Group, Department of Neurology and Division of Infectious Diseases, University of Colorado, Denver, Aurora.
Neurology. Clinical Practice
|January 7, 2017
Summary
Zika virus (ZIKV) can cause serious neurologic complications in both children and adults, including microcephaly and Guillain-Barré syndrome. Neurologists must be aware of these potential ZIKV disease risks, even with asymptomatic infections.
Area of Science:
- Neurology
- Infectious Diseases
- Virology
Background:
- Zika virus (ZIKV) was initially underestimated as a cause of neurological disease.
- Recent epidemics have highlighted significant neurological complications associated with ZIKV infections.
Approach:
- This review synthesizes current evidence on ZIKV-related neurological disorders.
- It examines transmission routes, diagnostic methods, and future research avenues for ZIKV.
Key Points:
- ZIKV disease is linked to congenital conditions like microcephaly and eye defects in infants.
- Adults may develop Guillain-Barré syndrome, uveitis, myelitis, and meningoencephalitis following ZIKV infection.
Conclusions:
- Most ZIKV infections are asymptomatic, but severe neurological sequelae can occur.
- Awareness of potential neurological complications in pediatric and adult populations is crucial for neurologists.
