Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Reflex Activity01:08

Reflex Activity

3.8K
A reflex activity is an automatic, involuntary response to specific stimuli. It is a part of our survival mechanism, designed to protect us from potential harm. For example, when a bright light suddenly shines into our eyes, we instinctively close them or look away. This is a simple reflex activity orchestrated by the nervous system without conscious thought or effort.
A reflex exam is a diagnostic procedure performed by a healthcare professional to evaluate the functionality of a patient's...
3.8K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.5K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.5K
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

11.0K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
11.0K
Glaucoma: Overview01:25

Glaucoma: Overview

1.6K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.6K
Somatic Spinal Reflexes01:22

Somatic Spinal Reflexes

6.4K
Somatic spinal reflexes are rapid, involuntary muscular responses to external stimuli that involve the somatic musculature and the spinal cord.
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...
6.4K
Focusing of Light in the Eye01:16

Focusing of Light in the Eye

6.9K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
6.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of bariatric surgery on headache frequency, duration and severity.

BMC surgery·2026
Same author

Relationship between headache types and severity with psychiatric comorbidity in adolescents.

Ideggyogyaszati szemle·2026
Same author

International evaluation of the SEIZUre Risk in Encephalitis (SEIZURE) score for predicting acute seizure risk.

BMJ open·2025
Same author

Effects of Bariatric Surgery on Sleep Disorder Symptoms and Sleep Quality.

Obesity surgery·2025
Same author

Discipline-specific responses to a complex migraine case: a vignette-based survey among neurologists, psychiatrists, and family physicians.

Frontiers in neurology·2025
Same author

Association of HLA-DRA, HLA-DQA1, and IL-6 gene variations with susceptibility to multiple sclerosis.

Molecular biology reports·2025

Related Experiment Video

Updated: Mar 9, 2026

Investigating Migraine-Like Behavior Using Light Aversion in Mice
05:23

Investigating Migraine-Like Behavior Using Light Aversion in Mice

Published on: August 11, 2021

4.6K

Blink reflex in migraine headache.

Zeynep Unal1, Fusun Mayda Domac2, Ece Boylu3

  • 1Neurology Department, Manisa State Hospital for Mental Health and Neurological Disorders, Manisa, Turkey.

Northern Clinics of Istanbul
|January 7, 2017
PubMed
Summary

The blink reflex test revealed prolonged nerve signal transmission times in migraine patients, indicating trigeminovascular system dysfunction. These findings support the trigeminovascular theory of migraine pathogenesis.

Keywords:
Blink reflexheadachemigraine

More Related Videos

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders
05:49

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders

Published on: November 1, 2024

1.3K
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

18.8K

Related Experiment Videos

Last Updated: Mar 9, 2026

Investigating Migraine-Like Behavior Using Light Aversion in Mice
05:23

Investigating Migraine-Like Behavior Using Light Aversion in Mice

Published on: August 11, 2021

4.6K
Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders
05:49

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders

Published on: November 1, 2024

1.3K
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

18.8K

Area of Science:

  • Neuroscience
  • Neurology
  • Physiology

Background:

  • Migraine pathogenesis is linked to trigeminovascular system activation.
  • The blink reflex (BR) test offers a method to assess trigeminal system function.
  • Neurophysiological changes in migraine patients can be studied via BR test latencies.

Purpose of the Study:

  • To evaluate neurophysiological changes in migraine patients using the blink reflex test.
  • To examine trigeminal system function in individuals with migraine compared to healthy controls.

Main Methods:

  • 40 migraine patients and 30 healthy controls underwent the blink reflex test.
  • Supraorbital nerve stimulation was performed, measuring early (R1) and late (R2) component latencies.
  • International Headache Society criteria were used for migraine diagnosis.

Main Results:

  • Migraine patients exhibited significantly longer R1 and R2 latencies compared to controls.
  • During an attack, patients showed prolonged latencies on the symptomatic side.
  • No significant correlation was found between latencies and gender, attack duration, frequency, or migraine type.

Conclusions:

  • Blink reflex test results suggest brainstem and trigeminovascular connection dysfunction in migraine patients.
  • These findings support the trigeminovascular theory of migraine.
  • The BR test is a valuable tool for investigating migraine pathophysiology.