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Related Concept Videos

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Related Experiment Video

Updated: Mar 9, 2026

Simultaneous Brightfield, Fluorescence, and Optical Coherence Tomographic Imaging of Contracting Cardiac Trabeculae Ex Vivo
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Compressive fluorescence imaging using a multi-core fiber and spatially dependent scattering.

Jaewook Shin, Bryan T Bosworth, Mark A Foster

    Optics Letters
    |January 7, 2017
    PubMed
    Summary

    We developed a novel fiber imaging system using compressed sensing and a scattering tip. This compact, bend-insensitive technology enables high-resolution imaging for minimally invasive procedures.

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    Area of Science:

    • Optics and Photonics
    • Biomedical Imaging
    • Computational Imaging

    Background:

    • Minimally invasive endomicroscopy requires compact and flexible imaging tools.
    • Traditional fiber imaging methods face limitations in resolution and space-bandwidth product.
    • Compressed sensing offers a powerful approach for reconstructing high-resolution images from limited data.

    Purpose of the Study:

    • To demonstrate a novel fiber-based imaging system for high-resolution microscopy.
    • To overcome the resolution limitations of conventional multi-core fiber imaging.
    • To develop a compact and robust imaging solution for endoscopic applications.

    Main Methods:

    • Utilizing a multi-core fiber with a scattering distal tip for illumination.
    • Employing compressed sensing signal acquisition for image reconstruction.
    • Generating structured speckle patterns through a coherent light source and diffuser.

    Main Results:

    • Achieved pixelation-free object image recovery.
    • Demonstrated a seven-fold increase in space-bandwidth product compared to the number of fiber cores.
    • The imaging system showed insensitivity to fiber bending.

    Conclusions:

    • The developed system offers a compact, flexible, and high-resolution imaging modality.
    • This technology is well-suited for advanced minimally invasive endomicroscopy.
    • The combination of multi-core fiber and compressed sensing significantly enhances imaging capabilities.