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A mitochondria-targeting fluorescent probe for the selective detection of glutathione in living cells
Xue-Liang Liu1, Li-Ya Niu2, Yu-Zhe Chen3
1School of Chemistry and biological Engineering, University of Science and Technology Beijing, Beijing 100083, P. R. China. yxyang@ustb.edu.cn.
Organic & Biomolecular Chemistry
|January 7, 2017
Abstract:
We report a fluorescent probe for the selective detection of mitochondrial glutathione (GSH). The probe, containing triphenylphosphine as a mitochondrial targeting group, exhibited ratiometric and selective detection of GSH over Cys/Hcy. The probe was used for imaging mitochondrial GSH in living HeLa cells.
