[Estrogen receptors in patients with brain tumors]

Estrogen receptor (ER) of brain tumors was assayed in 45 patients. In this series there were 39 cases contained ER, ranged from 0.7 to 188 fmol/mg protein of tumors (mean: 16.1 fmol/mg). The mean level of ER was 10.3 fmol/mg in 20 cases with meningiomas, 8.4 fmol/mg in 11 cases with gliomas, 51.1 fmol/mg in 5 cases with neurilemmomas, 10.5 fmol/mg in 3 cases with medulloblastomas, 16 fmol/mg in 2 organized hematomas due to ruptured AVM, 5.7 fmol/mg in a chordoma, 3.9 fmol/mg in a metastatic carcinoma from thyroid gland, and 0.8 fmol/mg in a cholesteatoma. The presence of ER in the latter several kinds of brain tumors have not been reported in previous literatures. The ER level of the tumors correlated with histological type of tumors, as well as the sex and age of the patients.