Related Experiment Video
Updated: Mar 9, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
PURTSCHER-LIKE RETINOPATHY ASSOCIATED WITH ADULT-ONSET STILL DISEASE
1Division of Rheumatology, Department of Medicine, Marshfield Clinic, Marshfield, Wisconsin.
Purpose:
To describe clinical, laboratory, and funduscopic data of a patient presenting with newly diagnosed adult-onset Still disease and Purtscher-like retinopathy.
Methods:
Observational case report.
Patient:
A 43-year-old man presented with a 3-week history of daily high-spiking fever, diffuse arthralgia and myalgia, sore throat, and a transient nonpruritic maculopapular rash. Two weeks from the onset of his illness, he developed a gradual decrease in visual acuity in both eyes. Fundoscopic examination showed multiple areas of retinal whitening, discrete superficial retinal hemorrhages, and few characteristic Purtscher flecken in the left eye.
Results:
The patient was diagnosed with adult-onset Still disease. We used high-dose corticosteroid therapy with complete resolution of adult-onset Still disease, but it was ineffective for recovery of vision.
Conclusion:
Clinicians should be aware of Purtscher-like retinopathy as a severe ophthalmic complication of adult-onset Still disease.

