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Updated: Mar 9, 2026

A Model to Simulate Clinically Relevant Hypoxia in Humans
Published on: December 22, 2016
Hypoxia Occurrence in a Military Aviator Below 3048 m
Introduction:
Despite technological advances, hypoxia remains a concern in aviation. Hypoxia can present with a vast array of symptoms that are unique to each aviator. Military aviators undergo hypoxia awareness trainings to learn their unique constellation of hypoxia symptoms.
Case Report:
This case report describes a military aviator who was flying in a B1 when the cabin depressurized. While performing the emergency checklist, the aviator was moving about the cabin and began to experience hypoxia symptoms. His symptoms occurred at an altitude below 3048 m (10,000 ft), and his fellow crewmembers remained asymptomatic. Previous hypoxia awareness trainings enabled the aviator to recognize his symptoms as hypoxic. His symptoms resolved within seconds of applying supplemental oxygen via his facemask, and he did not have any recurrence of his symptoms.
Discussion:
Aviators reliably remember their hypoxic symptoms from previous hypoxia awareness trainings up to 4.5 yr later. This enables the aviator to quickly take action to correct his or her symptoms. While hypoxia is commonly thought to only occur at altitudes greater than 4267 m (14,000 ft), it can occur at lower altitudes, especially if it is compounded with the physiological changes from exercise.Tristan LR. Hypoxia occurrence in a military aviator below 3048 m. Aerosp Med Hum Perform. 2017; 88(1):61-64.
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