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Hair growth begins with the production of keratinocytes by the basal cells of the hair bulb. As new cells are deposited at the hair bulb, the hair shaft is pushed through the follicle toward the surface. Keratinization is completed as the cells are pushed to the skin surface to form the shaft of hair that is externally visible. The external hair is completely dead and composed entirely of keratin. Hair can be cut or shaven without damaging the hair structure because the cut is superficial. Most...
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Androgenetic Alopecia: Narrative Review of Current Therapies and Proposal of a Practical Algorithm for Pharmacological Treatment.

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A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
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New Treatments for Hair Loss.

S Vañó-Galván1, F Camacho2

  • 1Servicio de Dermatología, Unidad de Tricología, Hospital Universitario Ramón y Cajal, IRYCIS, Universidad de Alcalá, Madrid, España.

Actas Dermo-Sifiliograficas
|January 8, 2017
PubMed
Summary

This review covers new hair loss treatments for androgenetic alopecia, alopecia areata, and frontal fibrosing alopecia. It highlights advancements in medications, therapies, and surgical techniques for improved patient outcomes.

Keywords:
Alopecia androgénicaAlopecia areataAlopecia frontal fibrosanteAndrogenetic alopeciaDutasteridaDutasterideFrontal fibrosing alopeciaHair loss treatmentsLow-level laser therapyLáser de baja potenciaRuxolitinibTricologíaVía WntWnt pathway

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Area of Science:

  • Dermatology
  • Trichology

Background:

  • Hair loss is a common dermatological issue impacting patients' quality of life.
  • Recent years have seen significant advancements in hair loss treatment options.

Purpose of the Study:

  • To review and summarize recent therapeutic advancements for various types of hair loss.
  • To categorize new treatments for androgenetic alopecia, alopecia areata, and frontal fibrosing alopecia.

Main Methods:

  • Literature review of recent studies on hair loss treatments.
  • Categorization of treatments based on alopecia type.
  • Discussion of pharmacological, physical, regenerative, and surgical modalities.

Main Results:

  • Androgenetic alopecia treatments include novel oral and topical formulations, prostaglandin analogs, low-level laser therapy, and regenerative medicine (Wnt signaling, stem cells).
  • Alopecia areata management focuses on Janus kinase inhibitors.
  • Frontal fibrosing alopecia treatments involve antiandrogens and pioglitazone.
  • Advancements in robotic hair transplantation and follicular unit extraction techniques are also noted.

Conclusions:

  • A wide array of novel treatments are emerging for diverse hair loss conditions.
  • These advancements offer new hope and improved therapeutic options for patients suffering from hair loss.