Bone marrow biopsies performed by both the powered OnControl drill device and the Jamshidi needle produce adequate
Sarika Jain1, Mark Enzerra2, Rohtesh S Mehta2
1Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Objective:
The aim of our study was to evaluate the adequacy and quality of the bone marrow (BM) obtained by OnControl powered drill (P-group) and to compare it with manual procedure (M-group).
Design:
Retrospective analysis was done on 75 BM specimens; Jamshidi needle (n=44) and OnControl (n=31). Biopsy length after fixation, evaluable marrow length and total area, and fragmentation, aspiration and marrow dropout artefacts were compared.
Results:
Biopsies were sufficient for diagnosis in 38/44 cases (86%) in the M-group and in 26/31 cases (83%) in the P-group. The most common reason for suboptimal/inadequate biopsies was subcortical specimens (4/6) in the M-group and aspiration artefact (5/5) in the P-group. Average length after fixation, evaluable marrow length, evaluable marrow area was comparable. Aspiration artefact was minimal (<10%) in the majority of BM samples in the M-group (31/44), while 25/31 BM in the P-group showed >10% aspiration artefact, p<0.0001.
Conclusions:
Our study suggests that quality of biopsy cylinder and adequacy rate of the biopsy is comparable between both devices. OnControl device showed more aspiration artefact.
Insights
Bone marrow biopsy adequacy was comparable between the manual Jamshidi needle and the OnControl powered drill. However, the OnControl device resulted in a higher aspiration artefact rate.
Area of Science:
- Hematology
- Medical Devices
- Surgical Techniques
Background:
- Bone marrow biopsy is crucial for diagnosing hematological disorders.
- Traditional manual bone marrow biopsy methods can be invasive and may yield suboptimal specimens.
- Powered drills offer potential for improved bone marrow specimen acquisition.
Purpose of the Study:
- To compare the adequacy and quality of bone marrow specimens obtained using the OnControl powered drill versus a manual Jamshidi needle.
- To evaluate specific parameters such as biopsy length, evaluable marrow area, and artefacts.
Main Methods:
- Retrospective analysis of 75 bone marrow specimens.
- Comparison between specimens obtained by Jamshidi needle (n=44) and OnControl powered drill (n=31).
- Evaluation of biopsy length, evaluable marrow length and area, and artefacts (fragmentation, aspiration, marrow dropout).
Main Results:
- Adequacy for diagnosis was similar: 86% for manual (M-group) and 83% for powered drill (P-group).
- Common inadequacy reasons: subcortical specimens (M-group) and aspiration artefact (P-group).
- Aspiration artefact was significantly higher in the OnControl group (p<0.0001).
Conclusions:
- Bone marrow biopsy adequacy and quality are comparable between manual and powered drill methods.
- The OnControl powered drill is associated with a higher incidence of aspiration artefact.
- Both methods provide sufficient bone marrow specimens for diagnosis, with differing artefact profiles.
