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Related Concept Videos

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Clot Retraction and Fibrinolysis

After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.
Cardiac Catheterization I: Pre-Procedure Overview01:28

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Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
Cardiac Catheterization II: Right Heart Catheterization01:21

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Cardiac Catheterization III: Left Heart Catheterization01:24

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Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
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Related Experiment Video

Updated: May 11, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

Thrombus apposition on catheter ablation injuries.

C Moro1, P Aragoncillo, P Jorge

  • 1Arrhythmia Unit, C. Ramon y Cajal, Madrid, Spain.

European Heart Journal
|September 1, 1989
PubMed
Summary

Catheter ablation can cause endocardial thrombus formation in 20% of injuries. Most thrombi are small (≤10 mm), with no link to energy or catheter type.

Area of Science:

  • Cardiovascular Pathology
  • Interventional Cardiology
  • Biomedical Engineering

Background:

  • Catheter ablation is a common treatment for cardiac arrhythmias.
  • Understanding potential complications, such as thrombus formation, is crucial for patient safety.

Purpose of the Study:

  • To determine the incidence and characteristics of endocardial thrombus formation following catheter ablation injuries.
  • To investigate potential correlations between thrombus formation and ablation parameters.

Main Methods:

  • Macroscopic and microscopic examination of catheter ablation-induced injuries in 16 mongrel dogs.
  • Ablation performed in various cardiac locations, including the right atrioventricular junction, aortic valve area, and ventricles.
  • Pathologic examination conducted one week post-ablation.

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Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter
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Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter

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Last Updated: May 11, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

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Published on: February 26, 2013

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology
10:46

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Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter
08:00

Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter

Published on: June 15, 2015

Main Results:

  • Thrombi were observed in 13 out of 64 (20%) ablation injuries.
  • The majority of thrombi (77%) measured ≤10 mm in diameter.
  • Thrombi were found in the tricuspid valve, aortic valve, subaortic region, and ventricular areas.
  • No correlation was found between thrombus formation and delivered energy or catheter polarity.

Conclusions:

  • Catheter ablation injuries have a 20% incidence of associated endocardial thrombus formation.
  • The majority of these thrombi are small and may pose minimal clinical risk.
  • Further research may explore the clinical significance of these findings in human patients.