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Diagnostic accuracy of echocardiography combined with chest CT in pulmonary hypertension

Adil Shujaat1, Abubakr A Bajwa2, Farah Al-Saffar3

  • 1Division of Pulmonary, Critical Care and Sleep Medicine, University at Buffalo, SUNY, Buffalo, NY, USA.

The Clinical Respiratory Journal
|January 8, 2017
PubMed

Insights

Combining transthoracic echocardiography (TTE) and computerized axial tomography (CT) improves pulmonary hypertension (PH) diagnosis. This combined approach offers better accuracy than individual imaging techniques for identifying PH.

Area of Science:

  • Cardiology
  • Radiology
  • Pulmonary Medicine

Background:

  • Transthoracic echocardiography (TTE) and computerized axial tomography (CT) are established imaging modalities.
  • Their complementary roles in diagnosing pulmonary hypertension (PH) warrant investigation.

Purpose of the Study:

  • To assess the diagnostic accuracy of combining TTE and chest CT for identifying PH.
  • To compare the combined diagnostic performance against individual imaging techniques.

Main Methods:

  • Retrospective review of 87 patients who underwent TTE, CT, and right heart catheterization (RHC).
  • PH defined by specific criteria on TTE (systolic pulmonary artery pressure >40 mm Hg or TR jet velocity >2.8m/s), CT (rPA >1 or dPA >30 mm), and RHC (mPAP >25 mm Hg).

Main Results:

  • A total of 87 patients were analyzed, with 75% prevalence of PH.
  • The combination of TTE's TR jet velocity and CT's rPA demonstrated high sensitivity (98%) and specificity (70%), with an ROC area under the curve of 0.84.

Conclusions:

  • The combined use of TTE and chest CT is superior to either modality alone for PH identification.
  • This integrated imaging strategy can aid in the diagnosis and exclusion of PH in diverse patient populations.
Abstract

Keywords:
chest CTdiagnosisechocardiographypulmonary hypertension

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