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Evaluation of size-exclusion chromatography for the analysis of phosphorothioate oligonucleotides

Atsuko Shimoyama1, Aki Fujisaka2, Satoshi Obika3

  • 1Analytical Research Laboratories, Technology, Astellas Pharma Inc., 5-2-3 Tokodai, Tsukuba-Shi, Ibaraki 300-2698, Japan; Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.

Journal of Pharmaceutical and Biomedical Analysis
|January 8, 2017
PubMed

Keywords:
Nucleic acids therapeuticsPhosphorothioate oligonucleotidesSize exclusion chromatography

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