Related Experiment Video
Updated: Mar 9, 2026

In Vivo Augmentation of Gut-Homing Regulatory T Cell Induction
Published on: January 22, 2020
Compliance with Dietary Guidelines and Increased Fortification Can Double Vitamin D Intake: A Simulation Study
Rajwinder K Harika1, Mariska Dötsch-Klerk, Peter L Zock
1Unilever Research and Development, Vlaardingen, The Netherlands.
Dietary strategies, including following Food-Based Dietary Guidelines (FBDG) and enhancing vitamin D fortification, can significantly increase vitamin D intake in adults. These combined approaches show potential to nearly double current vitamin D consumption.
Area of Science:
- Nutritional Science
- Public Health Nutrition
- Dietary Assessment
Background:
- Vitamin D is crucial for bone health and immune function, with low intake being a common concern.
- Recommended daily vitamin D intake is 10 µg/day, often difficult to achieve through diet alone, especially with limited sun exposure.
Purpose of the Study:
- To evaluate the potential of adhering to Food-Based Dietary Guidelines (FBDG) and increasing vitamin D fortification to meet recommended vitamin D intake levels.
- To assess the impact of these dietary strategies on vitamin D intake in adults across the UK, Netherlands, and Sweden.
Main Methods:
- Utilized national dietary survey data from adults in the UK, Netherlands, and Sweden.
- Simulated theoretical increases in vitamin D intake based on compliance with FBDG, enhanced fortification of common foods (margarines, milk), and a combination of both.
Main Results:
- Median usual vitamin D intake varied by country, with the UK at 2.4 µg/day, Netherlands at 3.4 µg/day, and Sweden at 5.3 µg/day.
- Compliance with FBDG for key sources (fish, margarine, meat) increased intake, while doubling fortification in margarines and milk also showed significant boosts.
- Combining FBDG compliance and enhanced fortification demonstrated the greatest potential, raising vitamin D intake to levels between 7.9-8.9 µg/day across the studied populations.
Conclusions:
- Dietary measures, specifically FBDG adherence and increased food fortification, hold substantial potential for improving vitamin D status in adults.
- These strategies can effectively increase vitamin D intake, contributing significantly towards achieving the recommended 10 µg/day, even with minimal sun exposure.
Related Concept Videos
Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Study Designs in Epidemiology
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
Bioavailability Study Design: Single Versus Multiple Dose Studies
Connective Tissue Cell Types
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
Vitamins