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Tumor Progression

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...

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Related Experiment Video

Updated: Mar 9, 2026

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies

Published on: July 28, 2020

Moving away from the tumor zone: A work in progress

Shyam Varadarajulu¹, Sundeep Lakhtakia²

¹Center for Interventional Endoscopy, Florida Hospital, Orlando, USA.

Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society

|January 10, 2017

Summary

No abstract available in PubMed .

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