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Analysis of Cardiomyocyte Development using Immunofluorescence in Embryonic Mouse Heart
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[Is there a structural principle of the myocardium?]
1Anatomisches und klinisch-morphologisches Institut der Universität, Witten/Herdecke.
Abstract:
Up to now neither by macroscopical nor histological findings a structural principle of the myocardium could be found. The tremendous complexity in the various courses of myocardium fibres and connective tissue as well as the pump diagram of the heart as a functional reference of all heart actions point to aspects of the heart function as a determined chaos. This could be demonstrated by a simple structural principle of the myocardium namely the myocardium fibres and connective tissue strands are arranged in the form of intermeshed hyperboloids. These could be of interest in the construction of artificial hearts. These new insights in form and function of the myocardium allow to discuss in a new way normal and pathological functions of the heart and to develop new therapeutical approaches.
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